CovidV2, Main, Exploration, bibRecord, 001109

Bilirubin encephalopathy in a domestic shorthair cat with increased osmotic fragility and cholangiohepatitis

Identifieur interne : 001109 ( Main/Exploration ); précédent : 001108; suivant : 001110

Bilirubin encephalopathy in a domestic shorthair cat with increased osmotic fragility and cholangiohepatitis

Auteurs : Elena T. Contreras [États-Unis] ; Urs Giger [États-Unis] ; Jennifer L. Malmberg [États-Unis] ; Jessica M. Quimby [États-Unis] ; Paula A. Schaffer [États-Unis]

Source :

Veterinary pathology [ 0300-9858 ] ; 2015.

RBID : PMC:4785093

Abstract

A 7-month-old female domestic shorthair (DSH) cat was diagnosed with chronic regenerative hemolytic anemia characterized by increased osmotic fragility (OF) of unknown etiology. At 13 months of age, the cat was evaluated for acute collapse. The cat was icteric with severe hyperbilirubinemia but no hematocrit changes. Severe obtundation and lateral recumbency progressed to tetraparesis and loss of proprioception in all four limbs, and a cerebellar or brainstem lesion was suspected. Post-mortem examination revealed suppurative cholangiohepatitis and acute neuronal necrosis in the nuclei of the brainstem and cerebellum, consistent with bilirubin encephalopathy. This is the first known occurrence of cholangiohepatitis and bilirubin encephalopathy in an adult cat with chronic hemolytic anemia. Although rare, bilirubin encephalopathy should be considered as a possible sequela to hyperbilirubinemia in adult patients. It remains unknown whether increased OF was related to the cholangiohepatopathy.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785093

DOI: 10.1177/0300985815603433
PubMed: 26354310
PubMed Central: 4785093

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Bilirubin encephalopathy in a domestic shorthair cat with increased osmotic fragility and cholangiohepatitis</title>
<author><name sortKey="Contreras, Elena T" sort="Contreras, Elena T" uniqKey="Contreras E" first="Elena T." last="Contreras">Elena T. Contreras</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO</wicri:regionArea>
<placeName><region type="state">Colorado</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Giger, Urs" sort="Giger, Urs" uniqKey="Giger U" first="Urs" last="Giger">Urs Giger</name>
<affiliation wicri:level="2"><nlm:aff id="A2">Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Malmberg, Jennifer L" sort="Malmberg, Jennifer L" uniqKey="Malmberg J" first="Jennifer L." last="Malmberg">Jennifer L. Malmberg</name>
<affiliation wicri:level="2"><nlm:aff id="A3">Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO</wicri:regionArea>
<placeName><region type="state">Colorado</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Quimby, Jessica M" sort="Quimby, Jessica M" uniqKey="Quimby J" first="Jessica M." last="Quimby">Jessica M. Quimby</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO</wicri:regionArea>
<placeName><region type="state">Colorado</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schaffer, Paula A" sort="Schaffer, Paula A" uniqKey="Schaffer P" first="Paula A." last="Schaffer">Paula A. Schaffer</name>
<affiliation wicri:level="2"><nlm:aff id="A2">Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">26354310</idno>
<idno type="pmc">4785093</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785093</idno>
<idno type="RBID">PMC:4785093</idno>
<idno type="doi">10.1177/0300985815603433</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">000746</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000746</idno>
<idno type="wicri:Area/Pmc/Curation">000746</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000746</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000592</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000592</idno>
<idno type="wicri:Area/Ncbi/Merge">000549</idno>
<idno type="wicri:Area/Ncbi/Curation">000549</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000549</idno>
<idno type="wicri:doubleKey">0300-9858:2015:Contreras E:bilirubin:encephalopathy:in</idno>
<idno type="wicri:Area/Main/Merge">001111</idno>
<idno type="wicri:Area/Main/Curation">001109</idno>
<idno type="wicri:Area/Main/Exploration">001109</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Bilirubin encephalopathy in a domestic shorthair cat with increased osmotic fragility and cholangiohepatitis</title>
<author><name sortKey="Contreras, Elena T" sort="Contreras, Elena T" uniqKey="Contreras E" first="Elena T." last="Contreras">Elena T. Contreras</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO</wicri:regionArea>
<placeName><region type="state">Colorado</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Giger, Urs" sort="Giger, Urs" uniqKey="Giger U" first="Urs" last="Giger">Urs Giger</name>
<affiliation wicri:level="2"><nlm:aff id="A2">Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Malmberg, Jennifer L" sort="Malmberg, Jennifer L" uniqKey="Malmberg J" first="Jennifer L." last="Malmberg">Jennifer L. Malmberg</name>
<affiliation wicri:level="2"><nlm:aff id="A3">Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO</wicri:regionArea>
<placeName><region type="state">Colorado</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Quimby, Jessica M" sort="Quimby, Jessica M" uniqKey="Quimby J" first="Jessica M." last="Quimby">Jessica M. Quimby</name>
<affiliation wicri:level="2"><nlm:aff id="A1">Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Department of Clinical Sciences, Veterinary Teaching Hospital, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO</wicri:regionArea>
<placeName><region type="state">Colorado</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schaffer, Paula A" sort="Schaffer, Paula A" uniqKey="Schaffer P" first="Paula A." last="Schaffer">Paula A. Schaffer</name>
<affiliation wicri:level="2"><nlm:aff id="A2">Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">États-Unis</country>
<wicri:regionArea>Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Veterinary pathology</title>
<idno type="ISSN">0300-9858</idno>
<idno type="eISSN">1544-2217</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">A 7-month-old female domestic shorthair (DSH) cat was diagnosed with chronic regenerative hemolytic anemia characterized by increased osmotic fragility (OF) of unknown etiology. At 13 months of age, the cat was evaluated for acute collapse. The cat was icteric with severe hyperbilirubinemia but no hematocrit changes. Severe obtundation and lateral recumbency progressed to tetraparesis and loss of proprioception in all four limbs, and a cerebellar or brainstem lesion was suspected. Post-mortem examination revealed suppurative cholangiohepatitis and acute neuronal necrosis in the nuclei of the brainstem and cerebellum, consistent with bilirubin encephalopathy. This is the first known occurrence of cholangiohepatitis and bilirubin encephalopathy in an adult cat with chronic hemolytic anemia. Although rare, bilirubin encephalopathy should be considered as a possible sequela to hyperbilirubinemia in adult patients. It remains unknown whether increased OF was related to the cholangiohepatopathy.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Colorado</li>
<li>Pennsylvanie</li>
</region>
</list>
<tree><country name="États-Unis"><region name="Colorado"><name sortKey="Contreras, Elena T" sort="Contreras, Elena T" uniqKey="Contreras E" first="Elena T." last="Contreras">Elena T. Contreras</name>
</region>
<name sortKey="Giger, Urs" sort="Giger, Urs" uniqKey="Giger U" first="Urs" last="Giger">Urs Giger</name>
<name sortKey="Malmberg, Jennifer L" sort="Malmberg, Jennifer L" uniqKey="Malmberg J" first="Jennifer L." last="Malmberg">Jennifer L. Malmberg</name>
<name sortKey="Quimby, Jessica M" sort="Quimby, Jessica M" uniqKey="Quimby J" first="Jessica M." last="Quimby">Jessica M. Quimby</name>
<name sortKey="Schaffer, Paula A" sort="Schaffer, Paula A" uniqKey="Schaffer P" first="Paula A." last="Schaffer">Paula A. Schaffer</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV2/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001109 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001109 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    CovidV2
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:4785093
   |texte=   Bilirubin encephalopathy in a domestic shorthair cat with increased osmotic fragility and cholangiohepatitis
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:26354310" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a CovidV2

This area was generated with Dilib version V0.6.33.
Data generation: Sat Mar 28 17:51:24 2020. Site generation: Sun Jan 31 15:35:48 2021

Serveur d'exploration Covid (26 mars)

Bilirubin encephalopathy in a domestic shorthair cat with increased osmotic fragility and cholangiohepatitis

Bilirubin encephalopathy in a domestic shorthair cat with increased osmotic fragility and cholangiohepatitis

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration Covid (26 mars)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.